Dr. Lindsay Parker

About

Currently I am an Australian Research Council Discovery Early Career Research Award (DECRA) Fellow and Lecturer in the Department of Molecular Sciences at Macquarie University. I have a PhD in Advanced Medicine from Macquarie University (2014) and a Bachelor of Science in Psychology from Michigan State University in the United States of America (2006). I worked in the field of cardiovascular neuroscience for 9 years, researching innervation of the heart and vasculature during hypertension at Michigan State University from 2006-2008 and then the neurochemistry of the stress response and methamphetamine addiction at Macquarie University from 2008-2012 throughout my PhD. Post-PhD I ran the Macquarie University Australian School of Advanced Medicine biomedical imaging unit from 2013 to 2015 and from 2015-2018 I held a post-doctoral research fellowship in the Centre for Nanoscale BioPhotonics under Professor Nicki Packer.





Publications




VISUALIZING NEUROINFLAMMATION WITH FLUORESCENCE AND LUMINESCENT LANTHANIDE BASED IN SITU HYBRIDIZATION.

Parker LM, Sayyadi N, Staikopoulos V, Shrestha A, Hutchinson MR, Packer NH (2019). (March 8 In Press Journal of Neuroinflammation)

UNDERSTANDING CELLULAR GLYCAN SURFACES IN THE CENTRAL NERVOUS SYSTEM.

Iqbal S, Ghanimi Fard M, Everest-Dass A, Packer NH, Parker LM (2019). doi:10.1042/BST20180330 (In Press, Biochemical Society Transactions)

THE EFFECT OF STREPTOZOTOCIN-INDUCED HYPERGLYCEMIA ON N-AND O-LINKED PROTEIN GLYCOSYLATION IN MOUSE OVARY.

Shathili AM, Brown HM, Everest-Dass AV, Tan TCY, Parker LM, Thompson JG, Packer NH (2018). Glycobiology 2018. https://doi.org/10.1093/glycob/cwy075.

MICROWAVE PRETREATMENT OF PARAMYLON ENHANCES THE ENZYMATIC PRODUCTION OF SOLUBLE Β 1,3-GLUCANS WITH IMMUNOSTIMULATORY ACTIVITY.

Gissibl A, Care A, Parker LM, Iqbal S, Hobba G, Nevalainen, Sunna A. Carbohydrate Polymers. 2018, 196:339-347. doi: 10.1016/j.carbpol.2018.05.038.

REDUCED BACKGROUND AUTOFLUORESCENCE FOR CELL IMAGING USING NANODIAMONDS AND LANTHANIDE CHELATES.

Cordina NM, Sayyadi N, Parker LM, Zhao Z, Everest-Dass A, Stoodley M, Brown L, Packer NH. Scientific Reports. 2018 Mar 14;8(1):4521. doi: 10.1038/s41598-018-22702-1.

METHAMPHETAMINE-INDUCED BEHAVIOURAL SENSITIZATION INDUCES SPECIFIC INTERNEURONAL MRNA PATHOLOGY ACROSS THE PRELIMBIC AND ORBITOFRONTAL CORTICES.

Wearne TA, Parker LM, Franklin JL, Goodchild AK, Cornish JL (2017). Progress in Neuropsychopharmacology & Biological Psychiatry. Jul 3;77:42-48. doi: 10.1016/j.pnpbp.2017.03.018

QUANTITATIVE PROTEOMIC ANALYSIS OF HUMAN TESTIS REVEALS SYSTEM-WIDE MOLECULAR AND CELLULAR PATHWAYS ASSOCIATED WITH NON-OBSTRUCTIVE AZOOSPERMIA.

Alikhani M, Mirzaei M, Sabbaghian M, Parsamatin P, Karamzadeh R, Adib S, Sodeifi N, Gilani MAS, Zabet-Moghaddam M, Parker LM, Wo Y, Haynes PA, Gourabi H, Baharvand H, and Salekdeh GH (2017). Journal of Proteomics Jun 6;162:141-154. doi: 10.1016/j.jprot.2017.02.007

NEUROCHEMISTRY OF NEURONS IN THE VENTROLATERAL MEDULLA ACTIVATED BY HYPOTENSION: ARE THE SAME NEURONS ACTIVATED BY GLUCOPRIVATION?

Parker LM, Le S, Wearne T, Hardwick K, Kumar NN, Robinson KJ, McMullan S, Goodchild AK (2017). Journal of Comparative Neurology Jun 15;525(9):2249-2264. doi: 10.1002/cne.24203.

GABAERGIC MRNA EXPRESSION IS DIFFERENTIALLY EXPRESSED ACROSS THE PRELIMBIC AND ORBITOFRONTAL CORTICES OF RATS SENSITIZED TO METHAMPHETAMINE: RELEVANCE TO PSYCHOSIS.

Wearne TA, Parker LM, Franklin JL, Goodchild AK, Cornish JL (2016). Neuropharmacology, 111, 107-118 doi:10.1016/j.neuropharm.2016.08.038

BRIGHTNESS AND PHOTOSTABILITY OF EMERGING RED AND NEAR-IR FLUORESCENT NANOMATERIALS FOR BIOIMAGING.

Reineck P, Francis A, Orth A, Lau DWM, Nixon-Luke RDV, Rastogi ID, Razali WAW, Cordina NM, Parker LM, Sreenivasan VKA, Brown LJ, Gibson BC (2016). Advanced Optical Materials. 4(10): p. 1549-1557 doi:10.1002/adom.201600212

Novel imaging tools for investigating the role of immune signaling in the brain

Jacobsen JHW, Parker LM, Staikopoulos V, Schartner E, Tsiminis G, Hutchinson MR, Mustafa S. Brain Behavior and Immunity (In Press)

Proteome Analysis of Ground State Pluripotency

Taleahmad S, Mirzaei M, Parker LM, Hassani SN, Mollamohammadi S, Sharifi-Zarchi A, Haynes PA, Baharvand H, Salekdeh G. Scientific Reports. Dec 16;5:17985, 2015.

Somatostatin 2A Receptors are not expressed on functionally identified respiratory neurons in the ventral respiratory column of the rat

Le S, Turner AJ, Parker LM, Burke PG, Kumar NN, Goodchild AK, McMullan S. Journal of Comparative Neurology. 524: 1384–1398, 2015

Chronic methamphetamine self-administration dysregulates oxytocin plasma levels and oxytocin receptor fibre density in the nucleus accumbens core and subthalamic nucleus of the rat

Baracz SJ, Parker LM, Suraev AS, Everett NA, Goodchild AK, McGregor IS, Cornish JL. JJournal of Neuroendocrinology, 28:4, 2015.

GABAergic mRNA expression is upregulated in the prefrontal cortex of rats sensitized to methamphetamine

Wearne TA, Parker LM, Franklin JL, Goodchild AK, Cornish JL. Behavioral Brain Research. Jan 15;297:224-30, 2015.

Hydralazine administration activates sympathetic preganglionic neurons whose activity mobilizes glucose and increases cardiovascular function

Parker LM, Damanhuri H, Fletcher S, McMullen S, Goodchild AK. Brain Research. 1604:25-34, 2015.

DDX3Y, a Male Specific Region of Y Chromosome Gene, may modulate neuronal differentiation

Vakilian H, Mirzaei M, Tabar MS, Pooyan P, Rezaee LH, Parker LM, Haynes PA, Gourabi H, H Baharvand, and Salekdeh GH. J. Proteome Res.14 (9), pp 3474–3483, 2015.

Distribution and neurochemical characterization of neurons in the rat ventrolateral medulla activated by glucoprivation

Parker LM, Kumar NK, Lonergan T, McMullen S, Goodchild AK. Brain Structure and Function. Jan;220(1):117-34, 2013

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Regional changes in cardiac and stellate ganglion norepinephrine transporter in DOCA-salt hypertension

Wehrwein EA, Novotny M, Swain GM, Parker LM, Esfahanian M, Spitsbergen JM, Habecker BA, and Kreulen DL. Autonomic Neuroscience: Basic and Clinical, 179(1-2):99-107, 2013.

 

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Neurochemical codes of sympathetic preganglionic neurons activated by glucoprivation

Parker LM, Kumar NK, Lonergan T, Goodchild AK Journal of Comparative Neurology. 521(12): 2703-18, 2013.

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Distribution and localization of Gα proteins in the rostral ventrolateral medulla of normotensive and hypertensive rats: focus on catecholaminergic neurons

Parker LM, Tallapragada VJ, Kumar NN, Goodchild AK Neuroscience 218:20-34, 2012.

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Neuropeptide coding of sympathetic preganglionic neurons; focus on adrenally projecting populations

Kumar, N.N., Allen, K., Parker, L., Damanhuri, H., Goodchild, A.K. Neuroscience170(3), 789-99, 2010.

Cardiac Norepinephrine Transporter protein is regionally expressed across heart chambers and is inversely correlated tochambernorepinephrine content

Wehrwein EA, Parker LM, Wright AA, Spitsbergen JM, Quaiserova-Mocko V, Novotny M, Swain GM, Kreulen DL.
Am J Physiol Regul Integr Comp Physiol. 295 (3), 2008.

Differential Regulation of NADPH Oxidase in Sympathetic and Sensory Ganglia in Deoxycorticosterone Acetate–Salt Hypertension

Cao X, Dai X, Parker LM, Kreulen DL.
Hypertension 50 (4), pp. 663-671, 2007.